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Lussier Research Group Research Resources

1. Software & Supplements of Publications

2. Seminars

3. K22 LM008308 grant publications

4. Lussielab Awards


Recent Publications

1.       Pantazatos SP, Li J, Pavlidis P, Lussier YA*. Integration of Neuroimaging and Microarray Datasets through Mapping and Model-Theoretic Semantic Decomposition of Unstructured Phenotypes. Cancer Informatics, 2009:8 7594. http://la-press.com/article.php?article_id=1484
·          Highly visible  (1153 readers in 6 months).


2.       Yang X, Huang Y, Chen J, Xie J, Sun X, Lussier YA*. Mechanism-Anchored Profiling derived from Epigenetic Networks Predicts Outcome in Acute Lymphoblastic Leukemia. BMC Bioinformatics 2009, 10(Suppl 9):S6 (17 September 2009).http://www.biomedcentral.com/1471-2105/10/S9/S6
·          Outstanding Paper Award from the American Medical Informatics Association.


3.       Yang X, Lee Y,  Fan H, Sun X*, Lussier YA*. Identification of common microRNA-mRNA regulatory biomodules in human epithelial cancers. Chinese Science Bulletin, in press http://www.springerlink.com/content/1001-6538/
http://128.248.3.165/publication/biomodule/microRNA_revised_resubmit_June262009.pdf


4.       Yang X§, Lee Y§, Huang Y, Chen J, Xing HR* , Lussier YA*.Stromal Microenvironment Processes Unveiled by Biological Component Analysis of Gene Expression in Xenograft Tumor Models. In press, BMC Bioinformatics.
·         "Selected for publication in BMC Bioinformatics as part of a special relationship between AMIA and BMC to recognize twelve exceptional 2010 TBI Summit papers."
·         Outstanding Paper Award from the American Medical Informatics Association.


5.       Lee Y§, Yang X§, Huang Y§, Fan H§, Zhang Q, Wu Y, Li J, Hasina R, Cheng C, Lingen M, Gerstein M, Weichselbaum R, Xing HR*,  Lussier YA*. MiR-204 suppresses tumor invasion by regulating molecular networks of cell adhesion and extracellular matrix remodelling. In press, PLoS Computational Biology.In press, PLOS Computational Biology.
·          One of the 24 best translational bioinformatics reports of 2009-10, by Russ Altman, in his review presented at the  2010 American Medical Informatics Association Summit on Translational Bioinformatics and on his blog http://rbaltman.wordpress.com/ (page 36 of the PDF file, URL below):
http://go2.wordpress.com/?id=725X1342&site=rbaltman.wordpress.com&url=http%3A%2F%2Ffiles.me.com%2Frussbaltman%2F71b0xt
·          Selected as late breaking news (5 selected) for highlight in The 2010 American Medical Informatics Association Summit on Translational Bioinformatics; S12, p.17 (program below). http://summit2010.amia.org/files/symposium2008/AMIA_TBI_On-Site_Program.pdf


6.       Chen J§, Sam L§, Huang Y§, Lee Y, Li J, Liu Y, Xing HR, Lussier YA*. Protein Interaction Network Underpins Concordant Prognosis Among Heterogeneous Breast Cancer Signatures. in press, Journal of Biomedical Informatics.
http://www.lussierlab.org/publication/networksignature/
http://dx.doi.org/10.1016/j.jbi.2010.03.009


7.       Yang X§, Huang Y§, Crowson M, Li J, Maitland M*, Lussier YA*. A Pharmacokinomics Study for Prediction of Molecular Mechanisms Underpinning the Side Effect of Kinase Inhibitors. (under review, submitted Sept 2009, Journal of Biomedical Informatics).


8.       Xinan Yang, Jianrong Li Younghee Lee, and Yves A. Lussier*. GO-Module: functional synthesis and improved interpretation of Gene Ontology patterns Journal of Biomedical Informatics Mar. 17, 2011 eprint. http://bioinformatics.oxfordjournals.org/content/early/2011/03/17/bioinformatics.btr142.full.pdf
http://www.lussierlab.org/publication/GO-Module/


Open Source Softwares

1.       DiscoveryMatch software -- Utilizing previous publication knowledge to suggest future co-publication efforts among related research fields. Source Code


2.       NLP systems software -- Pre and post processing utilities relating to the analysis of clinical narrative text using Natural Language Processing software. Source Code